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None of Emil Hallfredsson, Daniel Bogdanovic or Jamal Campbell-Ryce are likely to play. Hallfredsson would have been back in training after injury but illness has ruled him out whilst Bogdanovic has returned to training but isn't likely to be risked.
Nathan Doyle and former Burnley striker Andy Gray are both cup tied and are ruled out but Barnsley have confirmed that Iain Hume will play. He had three stitches and is bruised but it won't affect him.
On Saturday, Barnsley drew 0-0 at home to Swansea and they lined up: David Preece, Rob Kozluk, Stephen Foster, Darren Moore, Jacob Butterfield, Anderson De Silva, Adam Hammill, Julian Gray, Hugo Colace, Andy Gray, Iain Hume. Subs: Simon Heslop, Jonathan Macken, O'Neill Thompson, Onome Sodje, Tom Rusling.
Owen Coyle has confirmed there will be changes for Burnley but suggested nothing like as many as there were at Hartlepool. There have to be two. Chris McCann is ruled out with injury whilst David Nugent is cup tied after appearing for Portsmouth against Hereford in the last round.
It's difficult to even second guess what the line up will be but we will select from: Brian Jensen, Diego Penny, Tyrone Mears, Richard Eckersley, Clarke Carlisle, Andre Bikey, Michael Duff, David Edgar, Stephen Jordan, Christian Kalvenes, Brian Easton, Graham Alexander, Joey Gudjonsson, Kevin McDonald, Wade Elliott, Chris Eagles, Fernando Guerrero, Robbie Blake, Steven Fletcher, Martin Paterson, Steven Thompson, Jay Rodriguez.
Captain Steven Caldwell is back in training but it isn't likely that he'll be risked so soon after his return from injury.